To an increasing extent, the scientific literature is critical of the translatability of research results achieved with animal studies to humans, and of the reproducibility of research conducted with animals. More and more, that criticism now appears several times every quarter in the editorials, news and correspondence sections of leading scientific journals such as Nature and Science. Those contributions come up with multiple reasons and give extensive advice on what should be done to improve the translatability and reproducibility of animal experiments or how to replace them.
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